Pulmonary carcinoma with metastasis in a cat

9-years-old, domestic long-haired cat. Presented for weight loss, decreased appetite, lethargy, with elevated respiration rate and coughing episodes. A thoracic CT-scan was performed.

Domestic Long Hair Cat

Description

There is a mass like lesion, with irregular and ill-defined margins affecting the entire right accessory lung lobe and infiltrating the left caudal lung lobe (red arrows). This lesion has soft tissue attenuation, showing a slightly heterogeneous contrast enhancement. The lesion is visible as a consolidated area with presence of multiple air bronchograms embedded within the lesion, causing a mild mass effect over the lobar bronchi of the left caudal lung lobe, which is laterally displaced.

cat, thorax, lung lobe
cat, thorax, lung lobe
cat, thorax, lung lobe
cat, thorax, lung lobe

From left to right: pre and post-contrast images

In addition, the right middle and caudal lung lobes (blue and pink arrows respectively) are completely consolidated, with a slightly increased volume and presence of air bronchograms, with similar appearance compared to the previously described lesion. Cranial to this region, there is a subpleural lesion connecting with the right caudal lung lobe, which seems to infiltrate the caudal aspect of the right cranial lung lobe (yellow arrows). These lung lobes have a soft tissue attenuation with a mild and slightly heterogeneous contrast enhancement.

cat, thorax, lung lobe
cat, thorax, lung lobe
cat, thorax, lung lobe

In addition, at the aerated portions of the left caudal lung lobe, there are multiple, variable in size, ill-defined nodular lesions (pink arrows).

cat, thorax, lung lobe
cat, thorax, lung lobe

There is a moderate/marked enlargement of the tracheobronchial lymph nodes (green arrows), which show a reduced homogeneous contrast enhancement.

cat, thorax, lymph nodes
cat, thorax, lymph nodes

Diagnosis

  • Complete consolidation of the right middle, caudal and accessory lung lobes associated to a mass-like lesion, partially infiltrating as well the left caudal lung lobe and possibly the right cranial lung lobe. These findings are most likely consistent with a neoplastic process (primary pulmonary tumor – carcinoma, among others).
  • At least 3 small nodules in the left caudal lung lobe, adjacent to the previously described lesion, consistent with metastatic disease, most likely.
  • Moderate tracheobronchial lymphadenopathy, most likely metastatic.

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